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Structure of 62353-77-9
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Methyl 3-iodothiophene-2-carboxylate is a bench-stable, moisture-tolerant building block featuring a reactive iodine substituent at the 3-position of a thiophene ring. This electrophilic handle enables seamless coupling in palladium-catalyzed cross-coupling reactions. The ester functionality provides solubility and stability under standard conditions.
Methyl 3-iodothiophene-2-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its stable iodide functionality. The thiophene core provides excellent planarity and electronic properties for constructing advanced pharmaceutical scaffolds. Bench-stable and readily purified by flash chromatography, it facilitates efficient access to substituted thiophenes via Suzuki, Stille, or Negishi coupling protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: