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Structure of 6214-29-5
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(E)-3-Methoxyacrylic acid is a sterically constrained, electron-deficient enoate featuring a methoxy group at the β-position. This configuration enables direct participation in conjugate additions and Diels-Alder reactions under mild conditions. The compound exhibits enhanced stability compared to its α,β-unsaturated analogs, facilitating handling in synthetic workflows involving nucleophilic attack or polymerization initiation.
(E)-3-Methoxyacrylic acid serves as a versatile building block for conjugated systems, enabling efficient access to α,β-unsaturated esters and amides via standard coupling reactions. Its stabilized enolate character facilitates Michael additions and Diels-Alder cycloadditions, while the methoxy group enhances solubility and offers a handle for further derivatization. Bench-stable and readily purified by recrystallization, it functions reliably in synthetic sequences requiring controlled reactivity and functional group compatibility.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: