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Structure of 6213-89-4
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(E)-3-Bromoacrylic acid is a bench-stable, electron-deficient alkene featuring a conjugated bromo-acid functionality. This configuration enables direct incorporation into Michael addition reactions and cross-coupling protocols. The para-orientation of the halogen enhances reactivity in palladium-catalyzed transformations while maintaining compatibility with common protecting groups.
(E)-3-Bromoacrylic acid serves as a versatile building block for the synthesis of substituted acrylates and conjugated systems. Its well-defined stereochemistry enables reliable incorporation into Michael acceptors, heterocyclic scaffolds, and polymerizable monomers. The bromine substituent offers high functional group tolerance and facilitates subsequent cross-coupling reactions, including Suzuki-Miyaura and Stille couplings. Bench-stable and amenable to standard purification techniques, it functions effectively in both academic and industrial synthetic workflows.
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314-H318
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: