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CS-W001157 4
Total: USD 88.00

Tricaproin

  • CAS No. 621-70-5

  • Cat. No. CS-0185760
  • Purity≥98%
  • MDL No.MFCD00042905

*For research and further manufacturing use only, not for direct human use.

Tricaproin|CS-0185760

Structure of 621-70-5

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General Information

  • CAS No. 621-70-5
  • Cat. No. CS-0185760
  • Purity ≥98%
  • MDL No. MFCD00042905
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₃₈O₆
  • Molecular Weight 386.52
  • Synonym(s) Trihexanoin
  • SMILES CCCCCC(=O)OCC(COC(=O)CCCCC)OC(=O)CCCCC

Description

Cell permeable. A key intermediate in the biosynthesis of nitric oxide by constitutive nitric oxide synthase (cNOS). NOHA can be efficiently oxidized to nitric oxide and citrulline by cytochrome P450 system. A potent inhibitor of liver and macrophage arginase (Ki = 150 M).

Synthesis

  • Route1
    • In-stock
      Glycerol|CS-6964
      56-81-5
    • null|null
      142-62-1
    • ~96%
    • In-stock
      Tricaproin|CS-0185760
      621-70-5

    References

    • Prager, Rolf H.; Yurui, Zhang Australian Journal of Chemistry, 1989 , vol. 42, # 6 p. 1003 - 1005
  • Route2
    • In-stock
      Glycerol|CS-6964
      56-81-5
    • null|null
      142-62-1
    • ~%
    • Monocaproin|CS-1328559
      502-53-4
    • null|null
      70916-55-1
    • null|null
      17598-91-3
    • In-stock
      Tricaproin|CS-0185760
      621-70-5
    • null|null
      17598-92-4

    References

    • ChemSusChem, , vol. 6, # 7 p. 1224 - 1234

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302+H312+H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   78.9
  • LogP   4.7255
  • H_Acceptors   6
  • H_Donors   0
  • Rotatable_Bonds   17

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