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CS-W001157 4
Total: USD 88.00

N,N-Dibenzylhydroxylamine

  • CAS No. 621-07-8

  • Cat. No. CS-W014971
  • Purity≥95%
  • MDL No.MFCD00004772

*For research and further manufacturing use only, not for direct human use.

N,N-Dibenzylhydroxylamine|CS-W014971

Structure of 621-07-8

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General Information

  • CAS No. 621-07-8
  • Cat. No. CS-W014971
  • Purity ≥95%
  • MDL No. MFCD00004772
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₅NO
  • Molecular Weight 213.28
  • Synonym(s) Rubber Anti aging agent DBHA
  • SMILES ON(CC1=CC=CC=C1)CC2=CC=CC=C2

Application

N,N-Dibenzylhydroxylamine serves as a stable, bench-accessible hydroxylamine equivalent that facilitates reductive amination and oxime formation under mild conditions. Its dual benzyl protecting groups enhance solubility and reduce hydrolytic degradation, enabling reliable use in the synthesis of nitrogen-containing heterocycles and functionalized intermediates. Functions effectively in palladium-catalyzed coupling sequences and offers orthogonal reactivity for late-stage modifications in medicinal chemistry workflows.

Synthesis

  • Route1
    • Dibenzylamine Norepinephrine Impurity|CS-0229253
      103-49-1
    • ~98%
    • In-stock
      N,N-Dibenzylhydroxylamine|CS-W014971
      621-07-8

    References

    • Murray, Robert W.; Singh, Megh Synthetic Communications, 1989 , vol. 19, # 20 p. 3509 - 3522
  • Route2
    • null|null
      3376-26-9
    • ~82%
    • In-stock
      N,N-Dibenzylhydroxylamine|CS-W014971
      621-07-8

    References

    • Ueda, Masafumi; Miyabe, Hideto; Namba, Megumi; Nakabayashi, Toshiki; Naito, Takeaki Tetrahedron Letters, 2002 , vol. 43, # 24 p. 4369 - 4371
  • Route3

    References

    • Fernandes, Luciano; Fischer, Franciele L.; Ribeiro, Carolina W.; Silveira, Gustavo P.; Sa, Marcus M.; Nome, Faruk; Terenzi, Hernan Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 16 p. 4499 - 4502

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   23.47
  • LogP   3.078
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   4

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