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CS-W001157 4
Total: USD 88.00

N,2-Diphenylacetamide

  • CAS No. 621-06-7

  • Cat. No. CS-0149845
  • Molecule weight211.26
  • Purity≥98%
  • MDL No.MFCD00086905

*For research and further manufacturing use only, not for direct human use.

N,2-Diphenylacetamide|CS-0149845

Structure of 621-06-7

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General Information

  • CAS No. 621-06-7
  • Cat. No. CS-0149845
  • Purity ≥98%
  • MDL No. MFCD00086905
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₃NO
  • Molecular Weight 211.26
  • Synonym(s) Phenacetylanilide
  • SMILES O=C(NC1=CC=CC=C1)CC2=CC=CC=C2

Description

N,2-Diphenylacetamide features a bifunctional architecture with two aromatic rings flanking a key amide linkage, delivering enhanced stability and solubility in polar organic solvents. This structure supports integration into complex molecular scaffolds for pharmaceutical and materials applications.

Application

N,2-Diphenylacetamide serves as a stable, bench-ready building block for the synthesis of biaryl-containing heterocycles and pharmaceutical intermediates. Its dual phenyl substituents confer enhanced stability and favorable solubility in organic media, while the amide functionality enables straightforward functionalization via standard coupling or reduction protocols. The molecule functions effectively in multi-step syntheses requiring orthogonal reactivity and is compatible with common purification methods.

Synthesis

  • Route1
    • null|null
      74497-02-2
    • null|null
      103-80-0
    • ~10%
    • In-stock
      N,2-Diphenylacetamide|CS-0149845
      621-06-7

    References

    • Shi, Feng; Li, Jian; Li, Chunju; Jia, Xueshun Tetrahedron Letters, 2010 , vol. 51, # 46 p. 6049 - 6051
  • Route2

    References

    • Quan, Zheng-Jun; Xia, Hai-Dong; Zhang, Zhang; Da, Yu-Xia; Wang, Xi-Cun Applied Organometallic Chemistry, 2014 , vol. 28, # 2 p. 81 - 85
  • Route3
    • null|null
      74497-02-2
    • null|null
      101-41-7
    • ~92%
    • In-stock
      N,2-Diphenylacetamide|CS-0149845
      621-06-7

    References

    • Gustafsson, Tomas; Ponten, Fritiof; Seeberger, Peter H. Chemical Communications, 2008 , # 9 p. 1100 - 1102

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.1
  • LogP   2.8678
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   3

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