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Structure of 620611-27-0
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tert-Butyl 4-(aminomethyl)-4-fluoropiperidine-1-carboxylate delivers a fluorinated piperidine scaffold with a pendant primary amine, enabling direct functionalization in medicinal chemistry. The tert-butyl carbamate protects the amine during synthesis, offering stability and ease of handling under standard conditions. This building block integrates readily into bioactive molecules requiring constrained, electron-deficient heterocycles with tunable polarity.
tert-Butyl 4-(aminomethyl)-4-fluoropiperidine-1-carboxylate serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated piperidine scaffolds prevalent in bioactive molecules. The protected amine and fluorinated aliphatic center offer orthogonal reactivity, facilitating downstream functionalization via nucleophilic substitution or reductive amination. Its bench-stable nature and compatibility with standard purification methods make it ideal for multi-step synthesis and process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: