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CS-W001157 4
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2-Hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde

  • CAS No. 620595-36-0

  • Cat. No. CS-0088575
  • Purity≥97%
  • MDL No.MFCD11846347
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    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

2-Hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde|CS-0088575

Structure of 620595-36-0

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Description

This boronate-functional aldehyde integrates seamlessly into Suzuki-Miyaura coupling workflows, offering reliable stability under standard conditions. The ortho-hydroxyl group enables chelation in transition-metal catalysis, while the tetramethyl-dioxaborolane moiety ensures efficient cross-coupling with aryl halides.

Application

2-Hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The ortho-hydroxyl and aldehyde groups enable chelation-assisted coupling and facilitate downstream functionalization. Its stability under ambient conditions and ease of purification make it well-suited for iterative synthesis of complex phenolic scaffolds and biaryl architectures in medicinal chemistry and materials science applications.

General Information

  • CAS No. 620595-36-0
  • Cat. No. CS-0088575
  • Purity ≥97%
  • MDL No. MFCD11846347
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₇BO₄
  • Molecular Weight 248.08
  • Synonym(s) 2-Hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-benzaldehyde
  • SMILES CC(O1)(C)C(C)(C)OB1C2=CC(C=O)=C(O)C=C2

Computational Chemistry Data

  • TPSA   55.76
  • LogP   1.5039
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P501

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