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CS-W001157 4
Total: USD 88.00

Ethyl 4-amino-1-methyl-1H-imidazole-5-carboxylate

  • CAS No. 61982-18-1

  • Cat. No. CS-D1070
  • Purity≥98%
  • MDL No.MFCD11053610

*For research and further manufacturing use only, not for direct human use.

Ethyl 4-amino-1-methyl-1H-imidazole-5-carboxylate|CS-D1070

Structure of 61982-18-1

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General Information

  • CAS No. 61982-18-1
  • Cat. No. CS-D1070
  • Purity ≥98%
  • MDL No. MFCD11053610
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₁N₃O₂
  • Molecular Weight 169.18
  • Synonym(s) ethyl 5-amino-3-methyl-imidazole-4-carboxylate
  • SMILES O=C(C1=C(N)N=CN1C)OCC

Description

Ethyl 4-amino-1-methyl-1H-imidazole-5-carboxylate is a bench-stable heterocyclic building block featuring a methylated imidazole core with orthogonal functional handles. The electron-rich imidazole ring integrates seamlessly into synthetic routes requiring nitrogen-donor scaffolds, while the ethyl ester and primary amine groups enable sequential derivatization in medicinal chemistry and materials synthesis.

Application

Ethyl 4-amino-1-methyl-1H-imidazole-5-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to imidazole-based scaffolds. Its amino and ester functionalities support diverse transformations, including amidation, alkylation, and coupling reactions, with good bench stability and ease of purification. The molecule functions effectively in the construction of bioactive heterocycles relevant to medicinal chemistry and agrochemical research.

Synthesis

  • Route1
    • null|null
      62382-55-2
    • ~60%
    • In-stock
      Ethyl 4-amino-1-methyl-1H-imidazole-5-carboxylate|CS-D1070
      61982-18-1

    References

    • Abbott Laboratories Patent: US5326776 A1, 1994 ; US 5326776 A
  • Route2
    • null|null
      70183-93-6
    • ~%
    • In-stock
      Ethyl 4-amino-1-methyl-1H-imidazole-5-carboxylate|CS-D1070
      61982-18-1

    References

    • Journal of the Chemical Society, , p. 751,757
  • Route3
    • 1-Methyl-4-nitro-1H-imidazole-5-carbonitrile|CS-0144982
      40648-96-2
    • ~%
    • In-stock
      Ethyl 4-amino-1-methyl-1H-imidazole-5-carboxylate|CS-D1070
      61982-18-1

    References

    • Journal of the Chemical Society, , p. 751,757

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   70.14
  • LogP   0.179
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   2

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