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CS-W001157 4
Total: USD 88.00

4-Carboxyphenyldiamine

  • CAS No. 619-05-6

  • Cat. No. CS-D1364
  • Purity≥95%
  • MDL No.MFCD00007726

*For research and further manufacturing use only, not for direct human use.

4-Carboxyphenyldiamine|CS-D1364

Structure of 619-05-6

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General Information

  • CAS No. 619-05-6
  • Cat. No. CS-D1364
  • Purity ≥95%
  • MDL No. MFCD00007726
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈N₂O₂
  • Molecular Weight None
  • Synonym(s) Benzoic acid, 3,4-diamino-
  • SMILES NC1=CC(C(O)=O)=CC=C1N

Description

4-Carboxyphenyldiamine features a para-substituted benzene ring bearing both amino and carboxylic acid functionalities, enabling dual reactivity in conjugation chemistries. This bifunctional scaffold facilitates integration into polymeric systems, bioconjugates, and functional materials under mild aqueous conditions. The molecule exhibits enhanced solubility and stability compared to unsubstituted analogs, supporting reliable performance in synthesis and formulation workflows.

Application

4-Carboxyphenyldiamine serves as a versatile building block for the synthesis of functionalized aromatic scaffolds, enabling efficient access to substituted anilines and heterocycles via standard coupling and cyclization protocols. Its dual amine and carboxylic acid functionalities offer orthogonal reactivity, facilitating modular derivatization in medicinal chemistry and materials science applications. The compound exhibits good bench stability and is readily purified by recrystallization, supporting reliable use in multi-step syntheses.

Synthesis

  • Route1

    References

    • US4399303 A1, ;
  • Route2

    References

    • WO2012/75053 A2, ; Page/Page column 84 ;
  • Route3

    References

    • Chemische Berichte, , vol. 2, p. 435 Chemische Berichte, , vol. 5, p. 199

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   89.34
  • LogP   0.5492
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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