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CS-W001157 4
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5-Hydroxyisophthalic acid

  • CAS No. 618-83-7

  • Cat. No. CS-W017132
  • Purity≥98%
  • MDL No.MFCD00002515

*For research and further manufacturing use only, not for direct human use.

5-Hydroxyisophthalic acid|CS-W017132

Structure of 618-83-7

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General Information

  • CAS No. 618-83-7
  • Cat. No. CS-W017132
  • Purity ≥98%
  • MDL No. MFCD00002515
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆O₅
  • Molecular Weight 182.13
  • Synonym(s) None
  • SMILES O=C(O)C1=CC(O)=CC(=C1)C(=O)O

Description

5-Hydroxyisophthalic acid features a rigid aromatic core with strategically positioned carboxylic acid and hydroxyl groups, enabling versatile coordination in metal-organic frameworks. This ortho-substituted diacid integrates readily into polymeric systems and serves as a key building block for functionalized materials requiring precise molecular architecture and enhanced solubility under standard conditions.

Synthesis

  • Route1

    References

    • ARDELYX, INC.; CHARMOT, Dominique; JACOBS, Jeffrey, W.; LEADBETTER, Michael, Robert; NAVRE, Marc; CARRERAS, Chris; BELL, Noah Patent: WO2010/78449 A2, 2010 ; Location in patent: Page/Page column 317 ; WO 2010/078449 A2
  • Route2

    References

    • Gelmont, Mark; Oren, Jakob Organic Process Research and Development, 2002 , vol. 6, # 5 p. 591 - 596
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    • In-stock
      5-Hydroxyisophthalic acid|CS-W017132
      618-83-7

    References

    • Journal of the Chemical Society, , p. 309,312

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   94.83
  • LogP   0.7886
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   2

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