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CS-W001157 4
Total: USD 88.00

Benzenesulfinic acid

  • CAS No. 618-41-7

  • Cat. No. CS-0156053
  • Purity≥97%
  • MDL No.MFCD00800458

*For research and further manufacturing use only, not for direct human use.

Benzenesulfinic acid|CS-0156053

Structure of 618-41-7

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General Information

  • CAS No. 618-41-7
  • Cat. No. CS-0156053
  • Purity ≥97%
  • MDL No. MFCD00800458
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆O₂S
  • Molecular Weight 142.18
  • Synonym(s) benzenesulphinic acid
  • SMILES C1=CC=C(C=C1)S(=O)O

Description

Benzenesulfinic acid offers a reactive sulfinyl group ideal for transition metal-catalyzed coupling reactions. This bench-stable reagent integrates readily into synthetic sequences requiring sulfur-functionalized intermediates, enabling efficient access to sulfonamide and sulfone derivatives under mild conditions.

Application

Benzenesulfinic acid serves as a reliable building block for sulfonamide and sulfonyl chloride synthesis, offering stable bench handling and compatibility with common protecting group strategies. It participates in well-documented transformations including oxidation to benzenesulfonic acid and coupling reactions under mild conditions, enabling efficient access to functionalized arenes and heterocyclic scaffolds relevant to medicinal chemistry and process development.

Synthesis

  • Route1
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      66693-07-0
    • ~%
    • In-stock
      Cinnamic acid|CS-W020005
      621-82-9
    • In-stock
      Benzenesulfinic acid|CS-0156053
      618-41-7

    References

    • American Chemical Journal, , vol. 5, p. 116
  • Route2
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      896-80-0
    • ~%
    • null|null
      119-27-7
    • In-stock
      Benzenesulfinic acid|CS-0156053
      618-41-7

    References

    • Journal of Organic Chemistry, , vol. 19, p. 1704,1706
  • Route3
    • N'-benzoylbenzenesulfonohydrazide|CS-0331447
      6631-28-3
    • In-stock
      Ethylene glycol,98%|CS-0015059
      107-21-1
    • ~%
    • null|null
      100-52-7
    • In-stock
      Benzenesulfinic acid|CS-0156053
      618-41-7

    References

    • Journal of the Chemical Society, , p. 584

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.2672
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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