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CS-W001157 4
Total: USD 88.00

5-Chlorofuran-2-carboxylic acid

  • CAS No. 618-30-4

  • Cat. No. CS-W005615
  • Purity≥97%
  • MDL No.MFCD00093272

*For research and further manufacturing use only, not for direct human use.

5-Chlorofuran-2-carboxylic acid|CS-W005615

Structure of 618-30-4

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General Information

  • CAS No. 618-30-4
  • Cat. No. CS-W005615
  • Purity ≥97%
  • MDL No. MFCD00093272
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₃ClO₃
  • Molecular Weight 146.53
  • Synonym(s) 5-Chloropyromucic acid
  • SMILES O=C(C1=CC=C(Cl)O1)O

Description

5-Chlorofuran-2-carboxylic acid features a chlorinated furan ring fused to a carboxylic acid group, delivering enhanced electron-withdrawing character and stability under standard reaction conditions. This structural motif enables direct integration into heterocyclic scaffolds for medicinal chemistry and materials applications.

Application

5-Chlorofuran-2-carboxylic acid serves as a versatile building block for heterocyclic synthesis, enabling efficient access to bioactive scaffolds through standard coupling and functionalization reactions. Its orthogonal reactivity profile supports direct derivatization at the carboxylic acid group while maintaining stability under common synthetic conditions. The chloro substituent provides a handle for further diversification via palladium-catalyzed cross-coupling or nucleophilic substitution, making it a practical choice for medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Computational Chemistry Data

  • TPSA   50.44
  • LogP   1.6312
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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