Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Chloro-2-(methylthio)pyrimidine-4-carboxylic acid

  • CAS No. 61727-33-1

  • Cat. No. CS-W002473
  • Purity≥95%
  • MDL No.MFCD00173907

*For research and further manufacturing use only, not for direct human use.

5-Chloro-2-(methylthio)pyrimidine-4-carboxylic acid|CS-W002473

Structure of 61727-33-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 61727-33-1
  • Cat. No. CS-W002473
  • Purity ≥95%
  • MDL No. MFCD00173907
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅ClN₂O₂S
  • Molecular Weight 204.63
  • Synonym(s) 5-Chloro-2-(methylsulfanyl)pyrimidine-4-carboxylic acid
  • SMILES CSc1ncc(c(n1)C(=O)O)Cl

Description

This pyrimidine carboxylic acid features a chloro group at C5 and a methylthio substituent at C2, creating a highly functionalized scaffold. The electron-withdrawing chlorine and sulfur-containing side chain enhance reactivity in coupling processes. This compound serves as a key intermediate for bioactive heterocycles, particularly in medicinal chemistry applications requiring tailored electronic and steric profiles.

Application

5-Chloro-2-(methylthio)pyrimidine-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of pyrimidine-based heterocycles through nucleophilic substitution and coupling reactions. The chloro group at C5 facilitates regioselective functionalization, while the methylthio and carboxylic acid moieties offer orthogonal reactivity for further derivatization. Its bench-stable nature and compatibility with standard synthetic protocols make it well-suited for API intermediate development and high-throughput screening campaigns.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   63.08
  • LogP   1.5501
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 61727-33-1 sigma61727-33-1 manufacturer61727-33-1 price61727-33-1 structure61727-33-1 SDSbuy 61727-33-161727-33-1 supplier61727-33-1 uses61727-33-1 molecular weightprice of 61727-33-161727-33-1 chemical name formula of 61727-33-1
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label