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CS-W001157 4
Total: USD 88.00

4-Hydroxy-3-nitrobenzoic acid

  • CAS No. 616-82-0

  • Cat. No. CS-W017067
  • Purity≥98%
  • MDL No.MFCD00007119

*For research and further manufacturing use only, not for direct human use.

4-Hydroxy-3-nitrobenzoic acid|CS-W017067

Structure of 616-82-0

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General Information

  • CAS No. 616-82-0
  • Cat. No. CS-W017067
  • Purity ≥98%
  • MDL No. MFCD00007119
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅NO₅
  • Molecular Weight 183.12
  • Synonym(s) 3-nitro-4-oxidobenzoate; 4-Hydroxy-3-nitrobenzoic acid
  • SMILES O=C(O)C1=CC=C(O)C([N+]([O-])=O)=C1

Description

4-Hydroxy-3-nitrobenzoic acid features a conjugated aromatic core bearing a hydroxyl group at the 4-position and a nitro substituent at the 3-position, enabling strong electron-withdrawing effects. This arrangement enhances reactivity in coupling reactions and facilitates incorporation into functionalized polymers and bioconjugates under standard conditions.

Synthesis

  • Route1

    References

    • CENTAURUS BIOPHARMA CO., LTD.; XIAO, Dengming; ZHU, Li; HU, Yuandong; YU, Rong; HU, Wei; ZHAO, Na; PENG, Yong; LUO, Hong; HAN, Yongxin Patent: WO2013/97773 A1, 2013 ; Location in patent: Paragraph 0266 ;
  • Route2
    • 4-Hydroxybenzoic acid  Cetirizine Impurity|CS-0167040
      99-96-7
    • ~98%
    • In-stock
      4-Hydroxy-3-nitrobenzoic acid|CS-W017067
      616-82-0

    References

    • Hosseini-Sarvari, Mona; Tavakolian, Mina Journal of Chemical Research, 2008 , # 12 p. 722 - 724
  • Route3
    • 4-Hydroxybenzoic acid  Cetirizine Impurity|CS-0167040
      99-96-7
    • ~48%
    • null|null
      51-28-5
    • In-stock
      4-Hydroxy-3-nitrobenzoic acid|CS-W017067
      616-82-0

    References

    • Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 22, # 11 p. 1129 - 1131

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   100.67
  • LogP   0.9986
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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