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CS-W001157 4
Total: USD 88.00

1-Iodo-2-methylbenzene

  • CAS No. 615-37-2

  • Cat. No. CS-W007394
  • Purity≥98%
  • MDL No.MFCD00001042

*For research and further manufacturing use only, not for direct human use.

1-Iodo-2-methylbenzene|CS-W007394

Structure of 615-37-2

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General Information

  • CAS No. 615-37-2
  • Cat. No. CS-W007394
  • Purity ≥98%
  • MDL No. MFCD00001042
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇I
  • Molecular Weight 218.04
  • Synonym(s) Toluene, o-iodo- (8CI)
  • SMILES CC1=CC=CC=C1I

Description

1-Iodo-2-methylbenzene features a methyl group ortho to an iodine atom, creating a sterically constrained and electron-deficient aromatic system. This configuration enhances its utility in palladium-catalyzed cross-coupling reactions, where the iodide serves as a highly reactive coupling handle. The compound exhibits bench-stable handling characteristics and compatibility with diverse reaction conditions.

Synthesis

  • Route1

    References

    • Yang, Haijun; Li, Yong; Jiang, Min; Wang, Junmei; Fu, Hua Chemistry - A European Journal, 2011 , vol. 17, # 20 p. 5652 - 5660
  • Route2
    • null|null
      95-49-8
    • ~49%
    • In-stock
      1-Iodo-2-methylbenzene|CS-W007394
      615-37-2

    References

    • McNeill, Eric; Barder, Timothy E.; Buchwald, Stephen L. Organic Letters, 2007 , vol. 9, # 19 p. 3785 - 3788
  • Route3
    • null|null
      108-88-3
    • ~29%
    • In-stock
      1-Iodo-2-methylbenzene|CS-W007394
      615-37-2
    • In-stock
      1-Iodo-4-methylbenzene|CS-W009210
      624-31-7

    References

    • Tetrahedron Letters, , vol. 30, # 13 p. 1649 - 1650

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315-H319
Precautionary Statements : P210-P264-P280-P302+P352-P362-P370+P378-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   2.59962
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

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