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CS-W001157 4
Total: USD 88.00

2-(4-(Benzyloxy)phenyl)ethanol

  • CAS No. 61439-59-6

  • Cat. No. CS-0156170
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(4-(Benzyloxy)phenyl)ethanol|CS-0156170

Structure of 61439-59-6

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General Information

  • CAS No. 61439-59-6
  • Cat. No. CS-0156170
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₆O₂
  • Molecular Weight 228.29
  • Synonym(s) p-Benzyloxyphenethyl alcohol
  • SMILES C1=CC=C(C=C1)COC2=CC=C(C=C2)CCO

Description

Antipain inhibits trypsin, papain, and catherpsins A and B (a reversible inhibitor of cysteine and serine proteases). It is used to evaluate the role of proteases in cell transformations. It is used to help identify new proteases.

Application

2-(4-(Benzyloxy)phenyl)ethanol serves as a versatile building block in medicinal chemistry and materials science, enabling efficient synthesis of aryl-ether-linked scaffolds. Its benzyloxy-protected phenolic functionality offers excellent stability during multi-step transformations, while the terminal primary alcohol facilitates straightforward derivatization via esterification, etherification, or coupling reactions. The molecule exhibits good bench stability and is readily purified by chromatography or crystallization, making it well-suited for high-throughput screening and process development workflows.

Synthesis

  • Route1

    References

    • AUSPEX PHARMACEUTICALS, INC. Patent: WO2007/139923 A1, 2007 ; Location in patent: Page/Page column 77 ; WO 2007/139923 A1
  • Route2
    • Tyrosol Metoprolol Impurity|CS-0214021
      501-94-0
    • null|null
      100-39-0
    • ~98%
    • In-stock
      2-(4-(Benzyloxy)phenyl)ethanol|CS-0156170
      61439-59-6

    References

    • Chu, Guo-Hua; Milano, Shawn; Kluth, Lisa; Rhodes, Michael; Boni, Riccardo; Johnson, David A.; Li, Pui-Kai Steroids, 1997 , vol. 62, # 7 p. 530 - 535
  • Route3
    • Tyrosol Metoprolol Impurity|CS-0214021
      501-94-0
    • null|null
      100-44-7
    • ~98%
    • In-stock
      2-(4-(Benzyloxy)phenyl)ethanol|CS-0156170
      61439-59-6

    References

    • Aberle, Nicholas; Catimel, Jenny; Nice, Edouard C.; Watson, Keith G. Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 13 p. 3741 - 3744

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   2.8004
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   5

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