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CS-W001157 4
Total: USD 88.00

3-Amino-3-phenylpropionic acid

  • CAS No. 614-19-7

  • Cat. No. CS-W002039
  • Purity≥97%
  • MDL No.MFCD00008064

*For research and further manufacturing use only, not for direct human use.

3-Amino-3-phenylpropionic acid|CS-W002039

Structure of 614-19-7

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General Information

  • CAS No. 614-19-7
  • Cat. No. CS-W002039
  • Purity ≥97%
  • MDL No. MFCD00008064
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁NO₂
  • Molecular Weight 165.19
  • Synonym(s) DL-β-Phenylalanine
  • SMILES NC(C1=CC=CC=C1)CC(O)=O

Description

3-Amino-3-phenylpropionic acid features a phenyl-substituted aliphatic chain with proximal amino and carboxylic acid functionalities, enabling direct incorporation into peptide scaffolds. This configuration supports structural rigidity and enhanced metabolic stability in bioactive peptide analogs.

Application

3-Amino-3-phenylpropionic acid serves as a valuable building block in the synthesis of bioactive molecules, particularly for constructing phenylalanine-derived scaffolds. Its α-amino carboxylic acid functionality enables straightforward peptide coupling and derivatization under standard conditions. The molecule exhibits good bench stability, facilitates purification via crystallization or chromatography, and demonstrates tolerance to diverse functional groups, making it well-suited for medicinal chemistry and process development workflows.

Synthesis

  • Route1
    • null|null
      1491159-18-2
    • ~74%
    • In-stock
      3-Amino-3-phenylpropionic acid|CS-W002039
      614-19-7

    References

    • Varga, Annamaria; Zaharia, Valentin; Nogradi, Mihaly; Poppe, Laszlo Tetrahedron Asymmetry, 2013 , vol. 24, # 21-22 p. 1389 - 1394
  • Route2
    • Tert-butyl (R)-3-amino-3-phenylpropanoate|CS-0272760
      161671-34-7
    • ~96%
    • In-stock
      3-Amino-3-phenylpropionic acid|CS-W002039
      614-19-7

    References

    • Davies, Stephen G.; Mulvaney, Andrew W.; Russell, Angela J.; Smith, Andrew D. Tetrahedron Asymmetry, 2007 , vol. 18, # 13 p. 1554 - 1566
  • Route3
    • null|null
      3646-50-2
    • ~%
    • In-stock
      3-Amino-3-phenylpropionic acid|CS-W002039
      614-19-7
    • In-stock
      3-Amino-3-phenylpropionic acid|CS-W002039
      614-19-7

    References

    • Pharmazie, , vol. 60, # 3 p. 181 - 185

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   1.1611
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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