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CS-W001157 4
Total: USD 88.00

Ethyl nicotinate

  • CAS No. 614-18-6

  • Cat. No. CS-W014344
  • Purity≥98%
  • MDL No.MFCD00006389

*For research and further manufacturing use only, not for direct human use.

Ethyl nicotinate|CS-W014344

Structure of 614-18-6

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General Information

  • CAS No. 614-18-6
  • Cat. No. CS-W014344
  • Purity ≥98%
  • MDL No. MFCD00006389
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₂
  • Molecular Weight 151.17
  • Synonym(s) Nicotinic acid ethylester; Ethyl nicotinate
  • SMILES O=C(OCC)C1=CN=CC=C1

Description

Trisphosphine is widely used in a variety of scientific research applications. It is used as a reagent in the synthesis of organic compounds, as a catalyst in the polymerization of vinyl monomers, and as a ligand in the coordination chemistry of transition metals. It is also used as a reagent in the synthesis of pharmaceuticals and in the analysis of biological samples.

Application

Ethyl nicotinate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to pyridine-based heterocycles and bioactive scaffolds. Its ester functionality offers stability and ease of purification, while the nicotinyl core supports diverse transformations including hydrogenation, nucleophilic substitution, and transition-metal-catalyzed couplings. Widely employed in medicinal chemistry and agrochemical synthesis, it functions as a key intermediate for functionalized pyridines and N-heterocyclic compounds.

Synthesis

  • Route1

    References

    • Li, Yan; Chen, Huan-Huan; Wang, Chu-Fei; Xu, Xiao-Lan; Feng, Yi-Si Tetrahedron Letters, 2012 , vol. 53, # 43 p. 5796 - 5799
  • Route2
    • In-stock
      3-Iodopyridine|CS-D1693
      1120-90-7
    • null|null
      64-17-5
    • null|null
      201230-82-2
    • ~95%
    • In-stock
      Ethyl nicotinate|CS-W014344
      614-18-6

    References

    • Kormos, Chad M.; Leadbeater, Nicholas E. Organic and Biomolecular Chemistry, 2007 , vol. 5, # 1 p. 65 - 68
  • Route3

    References

    • Shang, Rui; Fu, Yao; Li, Jia-Bin; Zhang, Song-Lin; Guo, Qing-Xiang; Liu, Lei Journal of the American Chemical Society, 2009 , vol. 131, p. 5738 - 5739

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3265
Class : 8
Packing Group : Ⅱ
Hazard Statements : H227-H314-H335
Precautionary Statements : P210-P260-P261-P264-P271-P280-P301+P330+P331-P304+P340-P363-P370+P378-P403-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   39.19
  • LogP   1.2583
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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