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CS-W001157 4
Total: USD 88.00

2-Bromo-1,8-naphthyridine

  • CAS No. 61323-17-9

  • Cat. No. CS-0235353
  • Purity≥98%
  • MDL No.MFCD00234385

*For research and further manufacturing use only, not for direct human use.

2-Bromo-1,8-naphthyridine|CS-0235353

Structure of 61323-17-9

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General Information

  • CAS No. 61323-17-9
  • Cat. No. CS-0235353
  • Purity ≥98%
  • MDL No. MFCD00234385
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅BrN₂
  • Molecular Weight 209.04
  • Synonym(s) 2-bromopyridino[2,3-b]pyridine
  • SMILES C1=CC2=C(N=C1)N=C(C=C2)Br

Description

2-Bromo-1,8-naphthyridine features a bromine substituent at the C2 position of a rigid, electron-deficient 1,8-naphthyridine core. This configuration enables direct functionalization in transition-metal-catalyzed cross-coupling reactions, facilitating the construction of complex heterocyclic architectures. The compound exhibits high stability under standard bench conditions and serves as a key scaffold for medicinal chemistry and materials development.

Application

2-Bromo-1,8-naphthyridine serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions due to its stable bromo functionality and electron-deficient heterocyclic core. Its structural rigidity and compatibility with diverse functional groups facilitate the construction of complex nitrogen-containing scaffolds relevant to medicinal chemistry and materials science. The compound exhibits good bench stability and is readily purified by recrystallization or column chromatography, supporting reliable integration into multi-step syntheses.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   2.3923
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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