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CS-W001157 4
Total: USD 88.00

4-Hydroxy-2-cyclopentenone

  • CAS No. 61305-27-9

  • Cat. No. CS-0139552
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Hydroxy-2-cyclopentenone|CS-0139552

Structure of 61305-27-9

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General Information

  • CAS No. 61305-27-9
  • Cat. No. CS-0139552
  • Purity ≥97%
  • MDL No. None
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₆O₂
  • Molecular Weight 98.10
  • Synonym(s) 4-Oxo-2-cyclopenten-1-ol
  • SMILES OC(C1)C=CC1=O

Description

4-Hydroxy-2-cyclopentenone features a reactive enone scaffold with a pendant hydroxyl group, enabling direct functionalization at the C4 position. This structure supports conjugate addition reactions and serves as a key intermediate in synthesizing bioactive cyclopentanoid frameworks. The molecule exhibits enhanced solubility in polar solvents compared to related cyclic ketones.

Application

4-Hydroxy-2-cyclopentenone serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted cyclopentane scaffolds. Its enone functionality supports Diels–Alder reactions, conjugate additions, and oxidation-sensitive transformations under controlled conditions. The hydroxyl group enhances polarity for purification and facilitates derivatization, while the cyclic α,β-unsaturated ketone system offers predictable reactivity in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   -0.1237
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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