Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Hydroxymethyl benzoic acid

  • CAS No. 612-20-4

  • Cat. No. CS-0028786
  • Purity≥97%
  • MDL No.MFCD02151998

*For research and further manufacturing use only, not for direct human use.

2-Hydroxymethyl benzoic acid|CS-0028786

Structure of 612-20-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 612-20-4
  • Cat. No. CS-0028786
  • Purity ≥97%
  • MDL No. MFCD02151998
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈O₃
  • Molecular Weight 152.15
  • Synonym(s) None
  • SMILES O=C(O)C1=CC=CC=C1CO

Description

2-Hydroxymethyl benzoic acid features a carboxylic acid group ortho to a hydroxymethyl substituent, enabling dual functionality for conjugation or derivatization. This arrangement supports integration into polymer backbones, chelating systems, or bioconjugate scaffolds under standard conditions. The molecule exhibits enhanced solubility and stability in aqueous and organic media, facilitating use in synthesis workflows requiring precise functional group placement.

Application

2-Hydroxymethyl benzoic acid serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized aromatic scaffolds. The ortho-hydroxymethyl group facilitates selective derivatization and acts as a handle for further transformations, including oxidation to aldehyde or carboxylic acid, while the carboxylic acid functionality supports amide coupling and esterification. Its bench-stable nature and compatibility with diverse reaction conditions make it ideal for use in medicinal chemistry and materials synthesis workflows.

Synthesis

  • Route1
    • null|null
      95-47-6
    • ~49%
    • In-stock
      2-Hydroxymethyl benzoic acid|CS-0028786
      612-20-4

    References

    • Debnath, Mainak; Dutta, Arpan; Biswas, Surajit; Das, Kalyan Kumar; Lee, Hon Man; Vicha, Jan; Marek, Radek; Marek, Jaromir; Ali, Mahammad Polyhedron, 2013 , vol. 63, p. 189 - 198
  • Route2
    • null|null
      95-47-6
    • ~7%
    • o-Toluic acid Tolvaptan  Impurity|CS-0229343
      118-90-1
    • In-stock
      2-Hydroxymethyl benzoic acid|CS-0028786
      612-20-4
    • In-stock
      Phthalic acid|CS-0009407
      88-99-3
    • Phthalaldehydic acid Butylphthalide  Impurity|CS-0228924
      119-67-5

    References

    • Tashiro, Yasutaka; Iwahama, Takahiro; Sakaguchi, Satoshi; Ishii, Yasutaka Advanced Synthesis and Catalysis, 2001 , vol. 343, # 2 p. 220 - 225
  • Route3

    References

    • Mannam, Sreedevi; Sekar Tetrahedron Letters, 2008 , vol. 49, # 15 p. 2457 - 2460

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   57.53
  • LogP   0.8771
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Hydroxymethyl benzoic acid sigma2-Hydroxymethyl benzoic acid manufacturer2-Hydroxymethyl benzoic acid price2-Hydroxymethyl benzoic acid structure2-Hydroxymethyl benzoic acid SDSbuy 2-Hydroxymethyl benzoic acid2-Hydroxymethyl benzoic acid supplier2-Hydroxymethyl benzoic acid uses2-Hydroxymethyl benzoic acid molecular weightprice of 2-Hydroxymethyl benzoic acid2-Hydroxymethyl benzoic acid chemical name formula of 2-Hydroxymethyl benzoic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label