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CS-W001157 4
Total: USD 88.00

1-Oxocyclopentane-2-carboxylic acid ethyl ester

  • CAS No. 611-10-9

  • Cat. No. CS-D1430
  • Purity≥94%
  • MDL No.MFCD00001412

*For research and further manufacturing use only, not for direct human use.

1-Oxocyclopentane-2-carboxylic acid ethyl ester|CS-D1430

Structure of 611-10-9

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General Information

  • CAS No. 611-10-9
  • Cat. No. CS-D1430
  • Purity ≥94%
  • MDL No. MFCD00001412
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂O₃
  • Molecular Weight 156.18
  • Synonym(s) Ethyl2-oxocyclopentanecarboxylate
  • SMILES O=C(C1C(CCC1)=O)OCC

Description

Phase-transfer benzylation reaction of ethyl 2-oxocyclopentanecarboxylate with benzyl bromide in microreactor has been investigated. Ethyl 2-oxocyclopentanecarboxylate participates in cobalt (II) Schiffs base complex catalyzed oxidation of primary and secondary alcohols.Ethyl 2-oxocyclopentanecarboxylate was used in stereoselective synthesis of ()-cis,cis-spiro[4.4]nonane-1,6-diol. It was also used in the synthesis of tanikolide.

Synthesis

  • Route1
    • Ethyl 2-(trifluoromethylsulfonyloxy)cyclopent-1-enecarboxylate|CS-0206813
      122539-74-6
    • In-stock
      Benzamide|CS-Z0019
      55-21-0
    • ~0%
    • null|null
      18227-13-9
    • In-stock
      1-Oxocyclopentane-2-carboxylic acid ethyl ester|CS-D1430
      611-10-9

    References

    • Wallace, Debra J.; Klauber, David J.; Chen, Cheng-Yi; Volante, Ralph P. Organic Letters, 2003 , vol. 5, # 24 p. 4749 - 4752
  • Route2
    • null|null
      16689-52-4
    • ~86%
    • In-stock
      1-Oxocyclopentane-2-carboxylic acid ethyl ester|CS-D1430
      611-10-9

    References

    • Chen, Fen-Er; Liu, Ji-Dong; Fu, Han; Peng, Zuo-Zhong; Shao, Lan-Ying Synthetic Communications, 2000 , vol. 30, # 13 p. 2295 - 2299
  • Route3
    • null|null
      78647-27-5
    • ~75%
    • In-stock
      1-Oxocyclopentane-2-carboxylic acid ethyl ester|CS-D1430
      611-10-9

    References

    • Yamada, Yasuji; Ishii, Toshihide; Kimura, Masayuki; Hosaka, Kunio Tetrahedron Letters, 1981 , vol. 22, # 14 p. 1353 - 1354

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   43.37
  • LogP   0.9187
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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