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CS-W001157 4
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(3-Hydroxy-cyclohexyl)carbamic acid tert-butyl ester

  • CAS No. 610302-03-9

  • Cat. No. CS-W003310
  • Purity≥95%
  • MDL No.MFCD06658389

*For research and further manufacturing use only, not for direct human use.

(3-Hydroxy-cyclohexyl)carbamic acid tert-butyl ester|CS-W003310

Structure of 610302-03-9

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General Information

  • CAS No. 610302-03-9
  • Cat. No. CS-W003310
  • Purity ≥95%
  • MDL No. MFCD06658389
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₁NO₃
  • Molecular Weight 215.29
  • Synonym(s) Tert-butyl (3-hydroxycyclohexyl)carbamate
  • SMILES OC1CCCC(C1)NC(=O)OC(C)(C)C

Description

This tert-butyl carbamate derivative features a cyclohexyl ring bearing a hydroxyl group and a carbamoyl moiety, offering a bench-stable, moisture-tolerant platform for synthesizing functionalized cyclohexane scaffolds. The protecting group facilitates selective deprotection under mild acidic conditions, enabling controlled installation of amine functionalities in complex molecule assembly.

Application

(3-Hydroxy-cyclohexyl)carbamic acid tert-butyl ester serves as a versatile chiral building block for the synthesis of cyclohexane-based scaffolds. The protected amine and hydroxyl functionalities enable sequential functionalization, while the tert-butyl carbamate group offers stability and ease of removal under mild acidic conditions. This compound facilitates access to bioactive heterocycles and intermediates in medicinal chemistry through well-established coupling and cyclization protocols.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS09
Signal Word : Warning
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.56
  • LogP   1.8146
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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