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CS-W001157 4
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5-Hydroxy-2-nitrobenzoic acid

  • CAS No. 610-37-7

  • Cat. No. CS-W017066
  • Purity≥97%
  • MDL No.MFCD00017566

*For research and further manufacturing use only, not for direct human use.

5-Hydroxy-2-nitrobenzoic acid|CS-W017066

Structure of 610-37-7

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General Information

  • CAS No. 610-37-7
  • Cat. No. CS-W017066
  • Purity ≥97%
  • MDL No. MFCD00017566
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅NO₅
  • Molecular Weight 183.12
  • Synonym(s) Benzoic acid, 5-hydroxy-2-nitro-
  • SMILES O=C(O)C1=CC(O)=CC=C1[N+]([O-])=O

Description

5-Hydroxy-2-nitrobenzoic acid features a conjugated system with electron-withdrawing nitro and carboxylic acid groups flanking a phenolic hydroxyl, enabling selective functionalization in synthetic routes. This ortho-substituted architecture enhances reactivity in coupling processes and facilitates incorporation into bioactive scaffolds under mild conditions.

Synthesis

  • Route1

    References

    • Bertrand, Helene; Guillot, Regis; Teulade-Fichou, Marie-Paule; Fichou, Denis Chemistry - A European Journal, 2013 , vol. 19, # 43 p. 14654 - 14664
  • Route2

    References

    • Madani, Hadi; Thompson, Andrew S; Threadgill, Michael D Tetrahedron, 2002 , vol. 58, # 40 p. 8107 - 8111
  • Route3

    References

    • Journal of the Chinese Chemical Society, , vol. 52, # 3 p. 581 - 588

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   100.67
  • LogP   0.9986
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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