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CS-W001157 4
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Ethyl 2-methyl-3-oxobutanoate

  • CAS No. 609-14-3

  • Cat. No. CS-W004822
  • Purity≥95%
  • MDL No.MFCD00009164

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-methyl-3-oxobutanoate|CS-W004822

Structure of 609-14-3

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General Information

  • CAS No. 609-14-3
  • Cat. No. CS-W004822
  • Purity ≥95%
  • MDL No. MFCD00009164
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₂O₃
  • Molecular Weight 144.17
  • Synonym(s) α-Methyl acetoacetic acetate
  • SMILES CC(C(C)C(OCC)=O)=O

Description

Azido-PEG1-t-butyl ester is a azide containing molecules. it can react with alkyne, such as BCN, DBCO via Click Chemistry to yield a stable triazole linkage.

Application

Ethyl 2-methyl-3-oxobutanoate serves as a versatile β-keto ester building block in synthetic organic chemistry, enabling efficient construction of substituted pyrans, cyclohexanones, and heterocyclic scaffolds via Claisen condensations, Michael additions, and aldol-type reactions. Its bench-stable nature and compatibility with diverse functional groups facilitate straightforward purification and integration into multi-step syntheses.

Synthesis

  • Route1
    • In-stock
      Ethyl acetoacetate|CS-0016216
      141-97-9
    • null|null
      74-88-4
    • ~93%
    • In-stock
      Ethyl 2-methyl-3-oxobutanoate|CS-W004822
      609-14-3

    References

    • Ravia, Silvana P.; Carrera, Ignacio; Seoane, Gustavo A.; Vero, Silvana; Gamenara, Daniela Tetrahedron Asymmetry, 2009 , vol. 20, # 12 p. 1393 - 1397
  • Route2
    • null|null
      97383-81-8
    • ~99%
    • In-stock
      Ethyl 2-methyl-3-oxobutanoate|CS-W004822
      609-14-3

    References

    • Suzuki, Hitomi; Takaoka, Koji; Osuka, Atsuhiro Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 3 p. 1067 - 1068
  • Route3

    References

    • Journal of the American Chemical Society, , vol. 102, p. 4983

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   43.37
  • LogP   0.7746
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   3

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