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CS-W001157 4
Total: USD 88.00

5-Cyclopropylthiazol-2-amine

  • CAS No. 606092-87-9

  • Cat. No. CS-0054987
  • Purity≥97%
  • MDL No.MFCD14706999

*For research and further manufacturing use only, not for direct human use.

5-Cyclopropylthiazol-2-amine|CS-0054987

Structure of 606092-87-9

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General Information

  • CAS No. 606092-87-9
  • Cat. No. CS-0054987
  • Purity ≥97%
  • MDL No. MFCD14706999
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈N₂S
  • Molecular Weight 140.21
  • Synonym(s) 2-Thiazolamine,5-cyclopropyl-(9CI)
  • SMILES NC1=NC=C(C2CC2)S1

Description

5-Cyclopropylthiazol-2-amine features a cyclopropyl-substituted thiazole core with a primary amine at the 2-position, offering enhanced solubility and metabolic stability. This scaffold integrates readily into bioactive molecules, serving as a key building block in medicinal chemistry for kinase inhibitors and antimicrobial agents.

Application

5-Cyclopropylthiazol-2-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to thiazole-based scaffolds. Its cyclopropyl substituent enhances metabolic stability and modulates lipophilicity, while the primary amine facilitates downstream functionalization via coupling reactions. The compound exhibits good bench stability and is compatible with standard synthetic workflows, making it valuable for lead optimization and API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.6027
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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