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CS-W001157 4
Total: USD 88.00

5,6-Dihydropyridin-2(1H)-one

  • CAS No. 6052-73-9

  • Cat. No. CS-W006454
  • Purity≥97%
  • MDL No.MFCD19216835

*For research and further manufacturing use only, not for direct human use.

5,6-Dihydropyridin-2(1H)-one|CS-W006454

Structure of 6052-73-9

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General Information

  • CAS No. 6052-73-9
  • Cat. No. CS-W006454
  • Purity ≥97%
  • MDL No. MFCD19216835
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₇NO
  • Molecular Weight 97.12
  • Synonym(s) 1,5,6-Trihydropyridin-2-one
  • SMILES O=C1C=CCCN1

Description

5,6-Dihydropyridin-2(1H)-one features a reduced pyridinone core with enhanced nucleophilicity at the C5 position, enabling direct functionalization in synthetic transformations. This scaffold integrates readily into heterocyclic architectures and serves as a key intermediate in medicinal chemistry applications.

Application

5,6-Dihydropyridin-2(1H)-one serves as a versatile scaffold in medicinal chemistry, enabling efficient access to functionalized pyridine derivatives. Its enolizable carbonyl and conjugated diene system facilitate Diels-Alder reactions, nucleophilic additions, and transition-metal-catalyzed couplings. The compound exhibits bench stability and compatible functional group tolerance, supporting straightforward purification and integration into multi-step syntheses of heterocyclic drug candidates.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   29.1
  • LogP   0.0625
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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