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CS-W001157 4
Total: USD 88.00

Dimethyl pyridine-2,3-dicarboxylate

  • CAS No. 605-38-9

  • Cat. No. CS-W008590
  • Purity≥98%
  • MDL No.MFCD00186549

*For research and further manufacturing use only, not for direct human use.

Dimethyl pyridine-2,3-dicarboxylate|CS-W008590

Structure of 605-38-9

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General Information

  • CAS No. 605-38-9
  • Cat. No. CS-W008590
  • Purity ≥98%
  • MDL No. MFCD00186549
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉NO₄
  • Molecular Weight 195.17
  • Synonym(s) Dimethyl quinolinate; NSC 17026; Quinolinic acid dimethyl ester
  • SMILES O=C(OC)C1=CC=CN=C1C(OC)=O

Description

Finasteride is used as a inhibitor of steroid 5-a-reductase, antiandrogen, an intracellular enzyme that converts the androgen testosterone into 5α dihydrotestosterone.

Application

Dimethyl pyridine-2,3-dicarboxylate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized heterocycles and pharmaceutical intermediates. Its dual ester functionality exhibits excellent stability and compatibility with standard reaction conditions, facilitating selective transformations and orthogonal derivatization. The molecule functions as a key scaffold in the synthesis of bioactive compounds and transition metal catalysts, particularly in Pd-catalyzed cross-coupling processes.

Synthesis

  • Route1

    References

    • Paul, D. Brenton Australian Journal of Chemistry, 1984 , vol. 37, # 1 p. 87 - 94
  • Route2

    References

    • Korea Research Institute of Chemical Technology; Smithkline Beecham P.L.C. Patent: US5770597 A1, 1998 ;
  • Route3

    References

    • US5194430 A1, ; US 5194430 A

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H318-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   65.49
  • LogP   0.6548
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   2

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