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CS-W001157 4
Total: USD 88.00

4-Phenylquinoline

  • CAS No. 605-03-8

  • Cat. No. CS-0156410
  • Purity≥95%
  • MDL No.MFCD13689220

*For research and further manufacturing use only, not for direct human use.

4-Phenylquinoline|CS-0156410

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General Information

  • CAS No. 605-03-8
  • Cat. No. CS-0156410
  • Purity ≥95%
  • MDL No. MFCD13689220
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₁N
  • Molecular Weight 205.25
  • Synonym(s) None
  • SMILES C1=CC=C(C=C1)C2=CC=NC3=CC=CC=C23

Description

4-Phenylquinoline is a rigid, electron-rich heteroaromatic scaffold featuring a quinoline core fused to a phenyl ring. This structural arrangement enhances π-conjugation and planarity, promoting strong intermolecular interactions in organic semiconductors. The compound exhibits excellent thermal stability and serves as a key building block in the design of fluorescent probes and ligands for transition metal catalysis.

Application

4-Phenylquinoline serves as a privileged scaffold in medicinal chemistry, enabling the construction of diverse heterocyclic architectures. Its planar, electron-rich framework facilitates efficient Pd-catalyzed cross-coupling reactions and functions as a key building block in the synthesis of kinase inhibitors and other bioactive compounds. The molecule exhibits good bench stability and moderate solubility, simplifying purification and handling in multi-step synthetic sequences.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   3.9018
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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