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CS-W001157 4
Total: USD 88.00

(S)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane

  • CAS No. 60456-22-6

  • Cat. No. CS-W018133
  • Purity≥95%
  • MDL No.MFCD00273365

*For research and further manufacturing use only, not for direct human use.

(S)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane|CS-W018133

Structure of 60456-22-6

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General Information

  • CAS No. 60456-22-6
  • Cat. No. CS-W018133
  • Purity ≥95%
  • MDL No. MFCD00273365
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁ClO₂
  • Molecular Weight 150.60
  • Synonym(s) (S)-(-)-3-CHLORO-1,2-PROPANEDIOL ACETONIDE
  • SMILES CC1(C)OC[C@@H](CCl)O1

Application

(S)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane serves as a stable, bench-ready chiral building block for asymmetric synthesis. Its chloromethyl group enables efficient nucleophilic substitution and functionalization under mild conditions, while the 1,3-dioxolane ring provides excellent stability and compatibility with diverse reaction environments. This compound facilitates the construction of complex stereodefined intermediates in medicinal chemistry and natural product synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS05,GHS06
Signal Word : Danger
UN#: 1992
Class : 3 (6.1)
Packing Group : Ⅲ
Hazard Statements : H226-H301-H318
Precautionary Statements : P210-P233-P240-P241-P242-P243-P264-P270-P280-P330-P370+P378-P405-P501

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Computational Chemistry Data

  • TPSA   18.46
  • LogP   1.3767
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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