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8-Methoxy-1-methylquinolin-2(1H)-one

  • CAS No. 60443-14-3

  • Cat. No. CS-0547689
  • Molecule weight189.21
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

8-Methoxy-1-methylquinolin-2(1H)-one|CS-0547689

Structure of 60443-14-3

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General Information

  • CAS No. 60443-14-3
  • Cat. No. CS-0547689
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₁NO₂
  • Molecular Weight 189.21
  • Synonym(s) 8-Methoxy-1-methylquinolin-2-one
  • SMILES CN1C(=O)C=CC2=C1C(=CC=C2)OC

Synthesis

  • Route1
    • 8-Hydroxy-2(1H)-quinolinone Indacaterol  Impurity|CS-0229464
      15450-76-7
    • null|null
      77-78-1
    • ~44%
    • 8-Methoxy-1-methylquinolin-2(1H)-one|CS-0547689
      60443-14-3

    References

    • GLAXO GROUP LIMITED Patent: WO2008/6648 A1, 2008 ; Location in patent: Page/Page column 42-43 ;
  • Route2
    • null|null
      3063-30-7
    • ~38%
    • 8-Methoxy-1-methylquinolin-2(1H)-one|CS-0547689
      60443-14-3

    References

    • Gesto, C.; Cuesta, E. de la; Avendano, C. Synthetic Communications, 1990 , vol. 20, # 1 p. 35 - 39
  • Route3
    • null|null
      326479-54-3
    • ~%
    • 8-Methoxy-1-methylquinolin-2(1H)-one|CS-0547689
      60443-14-3

    References

    • Toda; Sakagami; Goan; Simakata; Saitoh; Horiguchi; Sano Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 12 p. 1854 - 1861

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

  • TPSA   31.23
  • LogP   1.5471
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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