Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Chloro-1-methylindoline-2,3-dione

  • CAS No. 60434-13-1

  • Cat. No. CS-0042983
  • Purity≥97%
  • MDL No.MFCD02956479

*For research and further manufacturing use only, not for direct human use.

5-Chloro-1-methylindoline-2,3-dione|CS-0042983

Structure of 60434-13-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 60434-13-1
  • Cat. No. CS-0042983
  • Purity ≥97%
  • MDL No. MFCD02956479
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆ClNO₂
  • Molecular Weight 195.60
  • Synonym(s) 5-Chloro-1-methylindole-2,3-dione
  • SMILES O=C1N(C)C2=C(C=C(Cl)C=C2)C1=O

Description

5-Chloro-1-methylindoline-2,3-dione is a bench-stable, electron-deficient heterocycle featuring a chlorinated indoline core with dual carbonyl functionalities. This structure enables direct participation in cycloaddition reactions and acts as a reactive scaffold for conjugate additions. The methyl group enhances solubility in organic solvents while the chlorine substituent modulates electronic properties for tailored reactivity.

Application

5-Chloro-1-methylindoline-2,3-dione serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted indole derivatives via cycloaddition and nucleophilic substitution reactions. Its electrophilic quinone moiety exhibits high reactivity toward amines and thiols, facilitating the construction of complex heterocyclic scaffolds. The molecule’s bench-stable nature and compatibility with diverse functional groups make it suitable for iterative synthesis workflows in medicinal chemistry and process development.

Synthesis

  • Route1
    • In-stock
      5-Chloroindoline-2,3-dione|CS-D1123
      17630-76-1
    • null|null
      74-88-4
    • ~90%
    • In-stock
      5-Chloro-1-methylindoline-2,3-dione|CS-0042983
      60434-13-1

    References

    • Journal of Heterocyclic Chemistry, , vol. 45, # 4 p. 969 - 973
  • Route2
    • null|null
      62903-71-3
    • ~79%
    • In-stock
      5-Chloro-1-methylindoline-2,3-dione|CS-0042983
      60434-13-1

    References

    • European Journal of Organic Chemistry, , vol. 2014, # 14 p. 2878 - 2882
  • Route3
    • null|null
      872305-97-0
    • ~67%
    • In-stock
      5-Chloro-1-methylindoline-2,3-dione|CS-0042983
      60434-13-1

    References

    • Journal of the American Chemical Society, , vol. 132, # 26 p. 8900 - 8902

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   37.38
  • LogP   1.4991
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Chloro-1-methylindoline-2,3-dione sigma5-Chloro-1-methylindoline-2,3-dione manufacturer5-Chloro-1-methylindoline-2,3-dione price5-Chloro-1-methylindoline-2,3-dione structure5-Chloro-1-methylindoline-2,3-dione SDSbuy 5-Chloro-1-methylindoline-2,3-dione5-Chloro-1-methylindoline-2,3-dione supplier5-Chloro-1-methylindoline-2,3-dione uses5-Chloro-1-methylindoline-2,3-dione molecular weightprice of 5-Chloro-1-methylindoline-2,3-dione5-Chloro-1-methylindoline-2,3-dione chemical name formula of 5-Chloro-1-methylindoline-2,3-dione
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label