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Structure of 60434-13-1
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5-Chloro-1-methylindoline-2,3-dione is a bench-stable, electron-deficient heterocycle featuring a chlorinated indoline core with dual carbonyl functionalities. This structure enables direct participation in cycloaddition reactions and acts as a reactive scaffold for conjugate additions. The methyl group enhances solubility in organic solvents while the chlorine substituent modulates electronic properties for tailored reactivity.
5-Chloro-1-methylindoline-2,3-dione serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted indole derivatives via cycloaddition and nucleophilic substitution reactions. Its electrophilic quinone moiety exhibits high reactivity toward amines and thiols, facilitating the construction of complex heterocyclic scaffolds. The molecule’s bench-stable nature and compatibility with diverse functional groups make it suitable for iterative synthesis workflows in medicinal chemistry and process development.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: