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CS-W001157 4
Total: USD 88.00

4,4',4''-Methanetriyltriphenol

  • CAS No. 603-44-1

  • Cat. No. CS-0138509
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4,4',4''-Methanetriyltriphenol|CS-0138509

Structure of 603-44-1

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General Information

  • CAS No. 603-44-1
  • Cat. No. CS-0138509
  • Purity ≥96%
  • MDL No. None
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₁₆O₃
  • Molecular Weight 292.33
  • Synonym(s) Tris(4-hydroxyphenyl)methane
  • SMILES OC1=CC=C(C(C2=CC=C(O)C=C2)C3=CC=C(O)C=C3)C=C1

Description

4,4',4''-Methanetriyltriphenol features a rigid, three-dimensional core anchored by a central methane bridge linking three phenolic rings. This triaryl structure delivers enhanced thermal stability and defined spatial orientation, making it valuable for constructing high-performance polymers and functionalized materials in organic synthesis.

Application

4,4',4''-Methanetriyltriphenol serves as a versatile triaryl building block for the synthesis of polyfunctional aromatic scaffolds. Its three phenolic hydroxyl groups enable sequential functionalization and orthogonally tunable reactivity, facilitating efficient construction of complex heterocycles and dendritic architectures. The molecule exhibits excellent bench stability and compatibility with standard protection/deprotection protocols, making it well-suited for iterative synthetic workflows in medicinal chemistry and materials science applications.

Synthesis

  • Route1
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      603-45-2
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      53153-46-1
    • In-stock
      4,4',4''-Methanetriyltriphenol|CS-0138509
      603-44-1

    References

    • Journal of the American Chemical Society, , vol. 103, # 4 p. 849 - 856
  • Route2
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      110-87-2
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      79-08-3
    • ~%
    • In-stock
      4,4',4''-Methanetriyltriphenol|CS-0138509
      603-44-1

    References

    • US2009/155714 A1, ;
  • Route3

    References

    • Berscheid, Ralf; Nieger, Martin; Voegtle, Fritz Chemische Berichte, 1992 , vol. 125, # 7 p. 1687 - 1696

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   60.69
  • LogP   3.9836
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   3

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