1H-Pyrrolo[3,2-c]pyridin-4-amine

Name: 1H-Pyrrolo[3,2-c]pyridin-4-amine
Brand: ChemScene
Availability: InStock
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CAS No. 60290-23-5
Cat. No. CS-W007170
Purity≥97%
MDL No.MFCD08690132

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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1H-Pyrrolo[3,2-c]pyridin-4-amine|CS-W007170

Structure of 60290-23-5

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General Information

CAS No. 60290-23-5
Cat. No. CS-W007170
Purity ≥97%
MDL No. MFCD08690132
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₇N₃
Molecular Weight 133.15
Synonym(s) 4-Amino-5-azaindole hydrochloride
SMILES NC1=NC=CC2=C1C=CN2

Description

1H-Pyrrolo[3,2-c]pyridin-4-amine features a fused heterocyclic core with a strategically positioned amine group, enabling direct incorporation into bioactive molecules. This scaffold exhibits favorable solubility and stability under standard conditions, facilitating efficient coupling reactions in medicinal chemistry workflows. The electron-rich pyrrolopyridine system supports diverse functionalization, making it a valuable building block for targeted drug discovery programs.

Application

1H-Pyrrolo[3,2-c]pyridin-4-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to biologically relevant scaffolds. Its nitrogen-rich framework exhibits favorable reactivity in Pd-catalyzed couplings and supports diverse functionalization at the 4-position. The compound demonstrates excellent bench stability and compatibility with common protecting group strategies, facilitating straightforward purification and integration into multi-step synthesis workflows.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 54.7
LogP 1.1451
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrrole compounds

Key Words

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1H-Pyrrolo[3,2-c]pyridin-4-amine

CAS No. 60290-23-5

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