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Structure of 600727-96-6
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This pyrazole-functionalized isonicotinic acid features two 1H-pyrazol-1-yl groups positioned at the 2 and 6 positions of the pyridine ring, creating a rigid, electron-rich scaffold ideal for coordination chemistry. The carboxylic acid moiety enables metal chelation, while the flanking heterocycles enhance solubility and stability in polar solvents. This structure supports applications in supramolecular assembly, luminescent materials, and catalytic ligand design.
2,6-Di(1H-pyrazol-1-yl)isonicotinic acid serves as a versatile building block in the synthesis of functionalized heterocycles and bioactive scaffolds. Its pyrazole substituents confer enhanced solubility and hydrogen-bonding capacity, while the isonicotinic acid core enables coupling reactions with amines and alcohols under standard conditions. The molecule exhibits good bench stability and facilitates purification via recrystallization, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: