Lot numbers can be found on the outside label of a product:
(R)-2-Hydroxypropanamide
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CAS No. 598-81-2
- Cat. No. CS-W016674
- Purity≥97%
- MDL No.MFCD00210310
*For research and further manufacturing use only, not for direct human use.
Structure of 598-81-2
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General Information
- CAS No. 598-81-2
- Cat. No. CS-W016674
- Purity ≥97%
- MDL No. MFCD00210310
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₃H₇NO₂
- Molecular Weight 89.09
- Synonym(s) (R)-(+)-Lactamide
- SMILES C[C@@H](O)C(N)=O
Description
(R)-2-Hydroxypropanamide features a chiral hydroxyl group adjacent to an amide functionality, enabling selective incorporation into peptide scaffolds and chiral auxiliaries. This bench-stable compound integrates readily into asymmetric synthesis workflows, offering reliable stereocontrol in pharmaceutical intermediates and functional materials.
Application
(R)-2-Hydroxypropanamide serves as a chiral building block for the synthesis of β-hydroxy amides and related bioactive molecules. Its stereochemically defined hydroxyl and amide functionalities enable selective derivatization in peptide-like scaffolds and heterocyclic systems. The compound exhibits good bench stability, facilitates straightforward purification, and functions effectively in standard coupling and protection protocols common to medicinal chemistry workflows.
Synthesis
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Route1
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78-97-7 - ~77%
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In-stock
598-81-2
References
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Jammot, Jacqueline; Pascal, Robert; Commeyras, Auguste Tetrahedron Letters, 1989 , vol. 30, # 5 p. 563 - 564
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Route2
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97-64-3
- ~%
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In-stock
598-81-2
References
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Journal of the Chemical Society, , p. 1028
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Route3
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617-57-2 - ~%
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In-stock
598-81-2
References
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Justus Liebigs Annalen der Chemie, , vol. 133, p. 262
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 63.32
- LogP -1.1475
- H_Acceptors 2
- H_Donors 2
- Rotatable_Bonds 1
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Key Words
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