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CS-W001157 4
Total: USD 88.00

1-Methylthiourea

  • CAS No. 598-52-7

  • Cat. No. CS-W011347
  • Purity≥97%
  • MDL No.MFCD00004938

*For research and further manufacturing use only, not for direct human use.

1-Methylthiourea|CS-W011347

Structure of 598-52-7

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General Information

  • CAS No. 598-52-7
  • Cat. No. CS-W011347
  • Purity ≥97%
  • MDL No. MFCD00004938
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂H₆N₂S
  • Molecular Weight 90.14
  • Synonym(s) N-Methylthiourea
  • SMILES CNC(N)=S

Description

1-Methylthiourea is a bench-stable, moisture-tolerant thioamide derivative featuring a methyl-substituted nitrogen atom that enhances nucleophilicity. This compound integrates readily into heterocyclic syntheses and serves as a selective sulfur donor in transition-metal-catalyzed transformations.

Application

1-Methylthiourea serves as a versatile sulfur-containing building block in synthetic organic chemistry, enabling efficient access to thiazole and thiadiazole heterocycles via cyclization reactions. Its moderate nucleophilicity and bench stability facilitate straightforward incorporation into diverse reaction sequences, while its compatibility with common protecting groups supports orthogonal functionalization in complex molecule synthesis.

Synthesis

  • Route1
    • null|null
      556-61-6
    • ~99%
    • In-stock
      1-Methylthiourea|CS-W011347
      598-52-7

    References

    • Tetrahedron, , vol. 56, # 36 p. 6899 - 6911
  • Route2
    • null|null
      37929-27-4
    • ~88%
    • In-stock
      1-Methylthiourea|CS-W011347
      598-52-7

    References

    • Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1013 - 1018
  • Route3
    • null|null
      27406-60-6
    • ~89%
    • In-stock
      1-Methylthiourea|CS-W011347
      598-52-7

    References

    • Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1013 - 1018

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06,GHS09
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅱ
Hazard Statements : H300-H411
Precautionary Statements : P264-P270-P273-P330-P391-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   -0.5506
  • H_Acceptors   1
  • H_Donors   2
  • Rotatable_Bonds   0

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