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CS-W001157 4
Total: USD 88.00

Biotin-PEG2-NHS ester

  • CAS No. 596820-83-6

  • Cat. No. CS-0114492
  • Purity≥95%
  • MDL No.MFCD11974976

*For research and further manufacturing use only, not for direct human use.

Biotin-PEG2-NHS ester|CS-0114492

Structure of 596820-83-6

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General Information

  • CAS No. 596820-83-6
  • Cat. No. CS-0114492
  • Purity ≥95%
  • MDL No. MFCD11974976
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₃₂N₄O₈S
  • Molecular Weight 500.57
  • Synonym(s) None
  • SMILES O=C(NCCOCCOCCC(ON1C(CCC1=O)=O)=O)CCCCC2SCC(C2N3)NC3=O

Description

Biotin-PEG2-NHS ester enables efficient conjugation to primary amines under physiological conditions. This water-soluble linker combines biotin’s high-affinity binding with a short PEG spacer that minimizes steric interference, delivering robust detection or immobilization in biochemical assays and protein labeling workflows.

Application

Biotin-PEG2-NHS ester serves as a versatile bifunctional linker for protein and biomolecule conjugation. The NHS ester moiety readily reacts with primary amines under physiological conditions, enabling efficient labeling. The short PEG2 spacer enhances solubility and reduces steric hindrance, while the biotin group provides high-affinity binding to streptavidin or avidin for detection, purification, or immobilization. Ideal for antibody-drug conjugates, immunoassays, and surface functionalization.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   152.37
  • LogP   -0.1411
  • H_Acceptors   9
  • H_Donors   3
  • Rotatable_Bonds   15

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