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CS-W001157 4
Total: USD 88.00

4,5-Pyridazinedicarboxylic acid

  • CAS No. 59648-14-5

  • Cat. No. CS-W020555
  • Purity≥97%
  • MDL No.MFCD06742784

*For research and further manufacturing use only, not for direct human use.

4,5-Pyridazinedicarboxylic acid|CS-W020555

Structure of 59648-14-5

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General Information

  • CAS No. 59648-14-5
  • Cat. No. CS-W020555
  • Purity ≥97%
  • MDL No. MFCD06742784
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄N₂O₄
  • Molecular Weight 168.11
  • Synonym(s) Pyridazine-4,5-dicarboxylic Acid
  • SMILES O=C(C1=C(C(O)=O)C=NN=C1)O

Description

4,5-Pyridazinedicarboxylic acid is a bifunctional heterocyclic diacid featuring a pyridazine core with carboxylic acid groups at the 4 and 5 positions. This configuration enables robust coordination in metal-organic frameworks and facilitates conjugation in bioactive molecule design. The compound exhibits enhanced solubility in polar solvents and stability under standard bench conditions, supporting its use in synthetic and materials chemistry workflows.

Application

4,5-Pyridazinedicarboxylic acid serves as a versatile building block in medicinal chemistry and materials science, enabling the synthesis of heterocyclic scaffolds through standard coupling and cyclization protocols. Its dual carboxylic acid functionality provides excellent handle for derivatization, including amide formation and metal chelation, while maintaining bench stability and compatibility with common purification techniques.

Synthesis

  • Route1

    References

    • Krapcho; Maresch; Helgason; Rosner; Hacker; Spinelli; Menta; Oliva Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 6 p. 1597 - 1606
  • Route2
    • In-stock
      N,N′-Diphenylthiourea|CS-W012992
      102-08-9
    • null|null
      17412-11-2
    • ~%
    • In-stock
      4,5-Pyridazinedicarboxylic acid|CS-W020555
      59648-14-5
    • null|null
      16005-58-6
    • null|null
      60206-59-9

    References

    • Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 11 p. 2491 - 2495
  • Route3
    • null|null
      17412-11-2
    • ~%
    • In-stock
      4,5-Pyridazinedicarboxylic acid|CS-W020555
      59648-14-5
    • null|null
      16005-58-6
    • null|null
      60206-59-9

    References

    • Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 11 p. 2491 - 2495

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   100.38
  • LogP   -0.127
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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