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Structure of 59608-97-8
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4-(Chloromethyl)thiazol-2-amine hydrochloride features a reactive chloromethyl group flanked by a thiazole ring and a primary amine, enabling efficient conjugation in bioorthogonal workflows. This bench-stable salt form enhances solubility and handling in aqueous reaction media, streamlining incorporation into peptide and small-molecule constructs.
4-(Chloromethyl)thiazol-2-amine hydrochloride serves as a versatile building block for thiazole-based scaffolds, enabling efficient functionalization via nucleophilic substitution. The chloromethyl group facilitates conjugation with amines, thiols, and heterocycles under mild conditions, while the amine functionality offers direct derivatization potential. Bench-stable and compatible with standard purification protocols, it functions effectively in the synthesis of bioactive heterocycles and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H302-H314
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Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: