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Structure of 59608-01-4
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This pyridyl-substituted propiolic acid features a conjugated alkyne-carboxylic acid motif that enables efficient coupling in click chemistry and transition metal-catalyzed transformations. The electron-deficient pyridine ring enhances reactivity in nucleophilic additions, while the terminal alkyne supports robust Sonogashira couplings. Bench-stable and moisture-tolerant, it serves as a versatile building block for bioconjugation and materials synthesis.
3-(Pyridin-3-yl)prop-2-ynoic acid serves as a versatile building block for conjugated systems, enabling efficient access to heterocyclic scaffolds via [2+2] cycloadditions and Sonogashira coupling reactions. Its terminal alkyne and carboxylic acid functionalities offer orthogonal reactivity, facilitating modular synthesis of bioactive molecules. The compound exhibits good bench stability and is readily purified by recrystallization, making it well-suited for iterative synthetic workflows in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: