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CS-W001157 4
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3-Chlorothiophene-2-carboxylic acid

  • CAS No. 59337-89-2

  • Cat. No. CS-0043862
  • Purity≥98%
  • MDL No.MFCD00043888

*For research and further manufacturing use only, not for direct human use.

3-Chlorothiophene-2-carboxylic acid|CS-0043862

Structure of 59337-89-2

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General Information

  • CAS No. 59337-89-2
  • Cat. No. CS-0043862
  • Purity ≥98%
  • MDL No. MFCD00043888
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₃ClO₂S
  • Molecular Weight 162.59
  • Synonym(s) 3-chlorothiophene-2-carboxylate
  • SMILES OC(=O)C1=C(Cl)C=CS1

Application

3-Chlorothiophene-2-carboxylic acid serves as a versatile building block in heterocyclic synthesis, enabling efficient access to functionalized thiophene scaffolds. Its carboxylic acid group facilitates direct amidation, esterification, and coupling reactions, while the chlorine substituent supports palladium-catalyzed cross-coupling transformations. The compound exhibits good bench stability and compatibility with common protecting group strategies, making it well-suited for medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.0997
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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