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CS-W001157 4
Total: USD 88.00

4-Amino-5-hydroxymethyl-2-(methylthio)pyrimidine

  • CAS No. 588-36-3

  • Cat. No. CS-0045797
  • Purity≥97%
  • MDL No.MFCD08236793

*For research and further manufacturing use only, not for direct human use.

4-Amino-5-hydroxymethyl-2-(methylthio)pyrimidine|CS-0045797

Structure of 588-36-3

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General Information

  • CAS No. 588-36-3
  • Cat. No. CS-0045797
  • Purity ≥97%
  • MDL No. MFCD08236793
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₉N₃OS
  • Molecular Weight 171.22
  • Synonym(s) Methioprim
  • SMILES CSC1=NC(N)=C(CO)C=N1

Synthesis

  • Route1

    References

    • VanderWel, Scott N.; Harvey, Patricia J.; McNamara, Dennis J.; Repine, Joseph T.; Keller, Paul R.; Quin III, John; Booth, R. John; Elliott, William L.; Dobrusin, Ellen M.; Fry, David W.; Toogood, Peter L. Journal of Medicinal Chemistry, 2005 , vol. 48, # 7 p. 2371 - 2387
  • Route2
    • Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate Avanafil  Impurity|CS-0228709
      5909-24-0
    • ~%
    • In-stock
      4-Amino-5-hydroxymethyl-2-(methylthio)pyrimidine|CS-0045797
      588-36-3

    References

    • Journal of Medicinal Chemistry, , vol. 48, # 7 p. 2371 - 2387
  • Route3

    References

    • Journal of Organic Chemistry, , vol. 21, p. 567,571

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   72.03
  • LogP   0.273
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   2

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