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CS-W001157 4
Total: USD 88.00

Ethyl 2-(4-fluorophenyl)acetate

  • CAS No. 587-88-2

  • Cat. No. CS-W022645
  • Purity≥98%
  • MDL No.MFCD08235152

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-(4-fluorophenyl)acetate|CS-W022645

Structure of 587-88-2

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General Information

  • CAS No. 587-88-2
  • Cat. No. CS-W022645
  • Purity ≥98%
  • MDL No. MFCD08235152
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₁FO₂
  • Molecular Weight 182.19
  • Synonym(s) Ethyl 4-fluorophenylacetate
  • SMILES C1=CC(=CC=C1CC(OCC)=O)F

Description

Ethyl 2-(4-fluorophenyl)acetate features a fluorinated aryl group that enhances metabolic stability and modulates electronic properties. This bench-stable ester integrates readily into pharmaceutical intermediates, serving as a key building block for bioactive molecules through C–C coupling and functional group interconversions.

Application

Ethyl 2-(4-fluorophenyl)acetate serves as a versatile building block in medicinal chemistry, enabling efficient construction of biaryl and heterocyclic scaffolds. Its benzylic ester functionality exhibits robust stability under standard synthetic conditions and tolerates a range of functional groups, facilitating downstream transformations such as reduction, hydrolysis, and coupling reactions. The para-fluoro substituent enhances metabolic stability and modulates electronic properties, making it a practical choice for the synthesis of pharmaceutically relevant intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   1.9313
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   3

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