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CS-W001157 4
Total: USD 88.00

2-Phenylpropan-2-amine

  • CAS No. 585-32-0

  • Cat. No. CS-W004689
  • Molecule weight135.21
  • Purity≥97%
  • MDL No.MFCD00134680

*For research and further manufacturing use only, not for direct human use.

2-Phenylpropan-2-amine|CS-W004689

Structure of 585-32-0

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General Information

  • CAS No. 585-32-0
  • Cat. No. CS-W004689
  • Purity ≥97%
  • MDL No. MFCD00134680
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃N
  • Molecular Weight 135.21
  • Synonym(s) α-Aminoisopropylbenzene
  • SMILES CC(N)(C1=CC=CC=C1)C

Description

Ornidazole is a drug that cures some protozoan infections. It has been investigated for use in Crohn's disease after bowel resection. It is indicated in treatment of mixed amoebiasis, mixed amoebic dysentery, mixed giardiasis, trichomoniasis, bacterial vaginosis, Sexually transmitted diseases, infections of gynaecology, lower respiratory tract infections, ENT, surgical and dental infections.

Application

2-Phenylpropan-2-amine serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of β-amino alcohol derivatives and pharmaceutically relevant heterocycles. Its tertiary amine functionality offers enhanced solubility and metabolic stability in drug candidates. The molecule exhibits excellent bench stability, facilitates straightforward purification via crystallization or distillation, and demonstrates broad functional group tolerance in standard coupling and reduction protocols.

Synthesis

  • Route1
    • null|null
      32366-26-0
    • ~96%
    • In-stock
      2-Phenylpropan-2-amine|CS-W004689
      585-32-0

    References

    • Metallinos, Costa; Nerdinger, Sven; Snieckus, Victor Organic Letters, 1999 , vol. 1, # 8 p. 1183 - 1186
  • Route2

    References

    • Bulletin de la Societe Chimique de France, , p. 2319 - 2324
  • Route3
    • null|null
      917-54-4
    • null|null
      100-47-0
    • ~92%
    • In-stock
      2-Phenylpropan-2-amine|CS-W004689
      585-32-0

    References

    • Engel; Pan; Ying; Alemany Journal of the American Chemical Society, 2001 , vol. 123, # 16 p. 3706 - 3715

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H412
Precautionary Statements : P264-P270-P273-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.8804
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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