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CS-W001157 4
Total: USD 88.00

Methyl 2-(hydroxymethyl)isonicotinate

  • CAS No. 58481-17-7

  • Cat. No. CS-W006249
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 2-(hydroxymethyl)isonicotinate|CS-W006249

Structure of 58481-17-7

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General Information

  • CAS No. 58481-17-7
  • Cat. No. CS-W006249
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₃
  • Molecular Weight 167.16
  • Synonym(s) 2-Hydroxymethyl-isonicotinic acid methyl ester
  • SMILES COC(=O)C1=CC=NC(CO)=C1

Description

4-Bromomandelic acid is used as a pharmaceutical intermediate. 4-bromomandelic acid is mainly used as an analytical reagent for zirconium.

Application

Methyl 2-(hydroxymethyl)isonicotinate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to pyridine-based scaffolds. The pendant hydroxymethyl group facilitates selective functionalization, including oxidation to carboxylic acid or conversion to ether and ester derivatives. Its methyl ester functionality supports orthogonal transformations, while the isonicotinate core provides compatibility with standard coupling and reduction protocols. Bench-stable and readily purified by flash chromatography, it functions effectively in medicinal chemistry lead optimization and heterocyclic synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   59.42
  • LogP   0.3605
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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