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Structure of 58458-10-9
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3-Amino-2-bromobenzotrifluoride is a fluorinated aromatic building block featuring ortho-halogen and amino functionalities. This electron-deficient scaffold enables direct coupling reactions in cross-coupling and C–H functionalization workflows. The trifluoromethyl group enhances metabolic stability and lipophilicity, making it valuable for medicinal chemistry and agrochemical development.
3-Amino-2-bromobenzotrifluoride serves as a versatile building block for pharmaceutical and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions due to its ortho-bromo functionality. The amino group provides direct access to diverse heterocyclic scaffolds and facilitates further derivatization. Its trifluoromethyl group enhances metabolic stability and modulates lipophilicity, while the molecule exhibits excellent bench stability and compatibility with standard purification methods.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: