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CS-W001157 4
Total: USD 88.00

H-2-Nal-OH

  • CAS No. 58438-03-2

  • Cat. No. CS-W008379
  • Purity≥98%
  • MDL No.MFCD00066087

*For research and further manufacturing use only, not for direct human use.

H-2-Nal-OH|CS-W008379

Structure of 58438-03-2

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General Information

  • CAS No. 58438-03-2
  • Cat. No. CS-W008379
  • Purity ≥98%
  • MDL No. MFCD00066087
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₃NO₂
  • Molecular Weight 215.25
  • Synonym(s) None
  • SMILES O=C(O)[C@@H](N)CC1=CC=C2C=CC=CC2=C1

Description

H-2-Nal-OH is a bench-stable, moisture-tolerant amino acid derivative featuring a hydroxylated naphthyl side chain. This structure integrates readily into peptide scaffolds, offering enhanced solubility and structural rigidity for applications in bioconjugation and medicinal chemistry.

Application

H-2-Nal-OH serves as a valuable building block in peptide synthesis, offering a rigidified, conformationally constrained alanine analog. Its indole side chain enables π–π stacking and hydrophobic interactions, enhancing binding affinity in bioactive peptides. The hydroxyl group provides a handle for selective derivatization, while the stability under standard coupling conditions facilitates efficient incorporation into diverse peptide scaffolds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   1.7942
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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